InvivoGen已經(jīng)從人源HEK293胚胎腎細(xì)胞系或人源A549肺癌細(xì)胞系中開發(fā)出一系列細(xì)胞系可用于滿足您對于COVID-19的相關(guān)研究。
它們被專門設(shè)計(jì)用來研究SARS-CoV-2感染以及開發(fā)新的針對病毒或隨后的促炎癥免疫反應(yīng)治療方法。
| 細(xì)胞系 | 產(chǎn)品名稱 | 概述 | 報(bào)告系統(tǒng) | 貨號 |
| COVID-19-RELATEDCELLLINES |
| HEK293?(human) | HEK-Blue?hACE2 | HumanACE2-expressingreporterCells | SEAP | hkb-hace2 |
| HEK-Blue?hACE2-TMPRSS2 | HumanACE2-TMPRSS2expressingreporterCells | SEAP | hkb-hace2tpsa |
| 293-SARS2-S-dfur | SARS-CoV-2spike(D614)?withaninactivefurin(dfur)cleavagesite | None | 293-cov2-sdf |
| 293-SARS2-S | SARS-CoV-2spike(D614)-expressingHEK293cells | None | 293-cov2-s |
| 293-hMyD88 | HEK293-derived'donor'celllineforcellfusion | None | 293-hmyd |
| A549??(human) | A549-hACE2 | HumanACE2ExpressingCells | None | a549-hace2 |
| A549-hACE2-TMPRSS2 | HumanACE2andTMPRSS2ExpressingCells | None | a549-hace2tpsa |
| A549-Dual?hACE2-TMPRSS2 | HumanACE2&TMPRSS2Expressing(NF-κB-SEAP&IRF-Lucia) | SEAP/Lucia | a549d-cov2r |
| A549-Dual?KO-MDA5hACE2-TMPRSS2 | HumanMDA5Knockout—ACE2&TMPRSS2Expressing | SEAP/Lucia | a549d-komda5-cov2r |
| A549-Dual?KO-RIG-IhACE2-TMPRSS2 | HumanRIG-IKnockout—ACE2&TMPRSS2Expressing | SEAP/Lucia | a549d-korigi-cov2r |
| A549-ASC-GFP-NLRP1 | HumanACE2,TMPRSS2&NLRP1lungreportercells | GFP | a549-ascov2-nlrp1 |
| A549-ASCOV2 | HumanACE2&TMPRSS2lungreportercells | GFP | a549-ascov2 |
InvivoGen提供了一套不斷擴(kuò)展的SARS-CoV-2刺突蛋白質(zhì)粒系列，用于細(xì)胞表達(dá)或構(gòu)建刺突蛋白假病毒 :
| 名稱 | 變種 |
|
| Original | Wuhan-Hu-1 (Clade 19) |  |
| G614 variant | Clade 20 |
| Alpha | B.1.1.7 variant | United Kingdom (Clade 20I) |
| Beta | B.1.351 variant | South Africa (Clade 20H) |
| Epsilon | B.1.429 variant | California (Clade 21C) |
| Gamma | P.1 variant | Brazil (Clade 20J) |
| Iota | B.1.526 variant | New York(Clade 21F) |
| Kappa | B.1.617.1 variant | India (Clade 21B) |
| Delta| B.1.617.2 variant | India (Clade 21B) |
| Lambda | C.37 variant | Peru (Clade GR/452Q.V1) |
| Mu | B.1.621 variant | Colombia (Clade 21H) |
| Omicron | B.1.1.529/BA.1 variant | South Africa (Clade 21K) |
| Omicron | BA.2 variant | South Africa (Clade 21L) |
| Omicron | BA.4/BA.5 variant | South Africa (Clades 22A & 22B)
|
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