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天然免疫學熱點領(lǐng)域科研抗體(AbD Serotec?)---巨噬細胞標志物抗體

2021-05-08
瀏覽次數(shù)： 2810
AbD Serotec公司是全球領(lǐng)先的巨噬細胞標志物抗體供應商，其生產(chǎn)的MCA497, Rat Anti Mouse F4/80 Clone CI:A3-1是著名的成熟小鼠巨噬細胞表面特異性標志物抗體，有將近400篇的文獻引用，提供多達30種的包裝形式，可用于FC、WB，IF、IHC等7種應用。AbD Serotec享有該克隆的專利，是該抗體唯一的商業(yè)化生產(chǎn)商。
MCA1957識別小鼠細胞表面macrosialin，為人CD68的同源物，是專門表達于組織巨噬細胞的一種重度糖基化的跨膜糖蛋白。
?天然免疫學熱點領(lǐng)域科研抗體(AbD Serotec?)---巨噬細胞標志物抗體

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小鼠淋巴結(jié)的免疫熒光染色；巨噬細胞用anti ? ? ? ?小鼠脾臟冰凍切片的免疫組化染色；紅髓中的
F4/80(MCA497PE)染成紅色，B細胞用anti C- ? ? ?巨噬細胞用anti CD68(MCA1957)染色
D79b(MCA1821A488)染成綠色，細胞核用D-
API復染，呈藍色

AbD Serotec公司提供的最受歡迎的巨噬細胞標志物抗體
?人巨噬細胞標志物抗體
?產(chǎn)品名稱
?克隆號
?產(chǎn)品編號
?形式
?CD11b
?ICRF44?
?MCA551
?Pur., A647, A700, Az. Fr., Biot., FITC, RPE, RPE-A647
?CD14?
?UCHM1
?MCA596
?Pur., A647, APC, Az. Fr., Biot., FITC, RPE
?CD14?
?TUK4?
?MCA1568?
?Pur., A647, A700, Biot., FITC, LE, PB, RPE, RPE-A647, ?RPE-A750
?CD14?
?MEM-18
?MCA2185
?Pur., FITC, RPE
?CD14?
?61D3
?MCA2804
?RPE-Cy5, RPE-Cy5.5
?CD163
?EDHu-1?
?MCA1853?
?Pur., FITC
?CD169?
?7-239?
?MCA2517
?Pur., A488, A647, FITC, LE, RPE
?CD200R?
?OX108?
?MCA2282?
?Pur., A488, A647, Biot., FITC, RPE
?CD204?
?Poly?
?AHP563?
?Serum
?CD206?
?15-2?
?MCA2155?
?Pur.
?CD209?
?MR-1
?MCA2318?
?Pur., A488, A647, Biot., FITC, LE, RPE
?CD31?
?WM59?
?MCA1738
?Pur., A647, Biot., FITC, RPE
?CD36?
?SM??
?MCA722?
?Pur., A647, Az. Fr., FITC
?CD68?
?514H12
?MCA1815?
?S/N
?CD68?
?KiM7
?MCA2375F
?FITC
?Dectin-1?
?BD6
?MCA4662
?Pur., A488, A647, FITC, RPE
?Dectin-1?
?GE2
?MCA4661?
?Pur., A488, A647, FITC, LE, RPE
?Macrophage?
?MAC387?
?MCA874?
?Pur., A488, FITC, LE, RPE
?小鼠巨噬細胞標志物抗體
?CD11b
?M1/70.15
?MCA74
?Pur., A488, A647, A700, Biot., FITC, LE, RPE, RPE-
?A647, RPE-A750, RPE-Cy5
?CD11b
?5C6
?MCA711
?Pur., FITC, LE, RPE
?CD115
?604B5
?2E11
?MCA1898 Pur., Az. Fr., RPE
?CD169
?MOMA-1
?MCA947
?Pur., S/N, A647, FITC
?CD169
?3D6.112
?MCA884
?Pur., FITC, LE
?CD200R
?OX-110
?MCA2281
?Pur., A488, A647, Biot., FITC, LE, RPE
?CD204
?2F8
?MCA1322
?Pur., A488, A647, Biot., FITC, LE, RPE
?CD206
?MR5D3
?MCA2235
?Pur., A488, A647, Biot., FITC, LE, RPE
?CD31
?ER-MP12
?MCA2388
?Pur., A488, A647, Biot., RPE, RPE-A647
?CD36
?MF3
?MCA2748
?Pur., A488, A647, FITC, LE, RPE
?CD68
?FA-11
?MCA1957
?Pur., A488, A647, A700, Az. Fr., Biot., FITC, RPE
?Dectin-1 ?
?2A11
?MCA2289
?Pur., A647, Biot., FITC, LE, RPE
?Dectin-2
?D2.11E4
?MCA2415
?Pur., A488, A647, Biot., FITC, LE, RPE
?F4/80
?CI:A3-1
?MCA497
?Pur., A488, A647, A700, APC, Biot., FITC, LE, PB, RPE, ? ?RPE-A647, RPE-A750, S/N
?Ly-6B.2
?7/4
?MCA771
?Pur., A647, A700, Biot., FITC, LE, RPE
?Ly-6C
?ER-MP20
?MCA2389
?Pur., A488, A647, Biot., RPE
?MARCO
?ED31
?MCA1849
?Pur., FITC, RPE
?TREM-1
?L5-B8.2A12.3A12
?MCA2578
?Pur., A488, A647, FITC, LE, RPE
?TREM-2
? 78.18
?MCA4772
?Pur., FITC, LE
?大鼠巨噬細胞標志物抗體
?CD11b
?OX-42
?MCA275
?Pur., A488, A647, A700, Biot., FITC, LE, PB, RPE, RPE-
?A647
?CD11b
?ED7
?MCA618R
?Pur.
?CD11b
?ED8
?MCA619
?Pur., FITC, RPE
?CD115
?604B52E11
?MCA1898
?Pur., Az. Fr., RPE
?CD163
?ED2
?MCA342
?Pur., A647, Biot., FITC, LE, RPE
?CD169
?ED3
?MCA343
?Pur.
?CD172a
?OX41
?MCA274
?Pur., Az. Fr., Biot, FITC, RPE
?CD172a
?ED9
?MCA620
?Pur., FITC, RPE
?CD200R1
?OX-102
?MCA1959
?Pur., Biot., FITC, LE, RPE
?CD31
TLD-3A12
?MCA1334
?Pur., A488, A647, Biot., FITC, LE, RPE
?CD68
?ED1
?MCA341
?Pur., A488, A647, A700, Biot., FITC, RPE


熒光多色染色試劑
?產(chǎn)品名稱
?克隆號
?產(chǎn)品編號
?形式
?Human CD45/CD14
?F10-89-4/UCHM1
?DC008
?FITC/RPE
?Mouse IgG2a/IgG2a?
?Negative Control
?DC013
? FITC/RPE
?Mouse Ly6C/CD31
?ERMP20/ERMP12
?DC053
?A488/RPE
?Mouse Ly6C/CD31
?ERMP20/ERMP12
?DC054
?A488/RPE-A647
?Mouse CD11b/CD115
?M1/70.15 / 604B5 2E11
?DC055
?A488/RPE
?Mouse Ly6C/CD115/CD11b
?ERMP20/604B52E11/M1/70.15
?TC015
?A488/RPE/RPE-A647
?Mouse Ly6C/CD115/CD31
?ERMP20/604B52E11/ERMP12
?TC016
?A488/RPE/RPE-A647
?Mouse Ly6C/CD115/CD31
?ERMP20/604B52E11/ERMP12
?TC017
?A488/RPE/A647
?Mouse?Ly6C/CD115/CD11b/CD31
?ERMP20/604B52E11/M1/70.15/ERMP12
?QC001
?A488/RPE/RPE-A647/A647


AbD Serotec公司?F4/80?產(chǎn)品參考文獻
1. Austyn, J.M. and Gordon, S. (1981) F4/80 , a monoclonal antibody directed specifically against the mouse macrophage.Eur. J. Immunol. 11: 805-815.
2. Hume, D.A., Perry, V.H., and Gordon, S. (1984) The Mononuclear Phagocyte System of the Mouse defined by Immunohistochemical Localisation of Antigen F4/80: Macrophages Associated with Epithelia.The Anatomical Record 210: 503-512.
3. Lee, S.H.?et al. (1985) Quantitative analysis of total macrophage content in adult mouse tissues. Immunochemical studies with monoclonal antibody F4/80.J. Exp. Med. 161: 475-489.
4. Gordon, S.?et al. (1992) Antigen markers of macrophage differentiation in murine tissues.
Curr. Top. Micro. Immunol. 181: 1-37.
5. Uaesoontrachoon, K.?et al.?(2013) Osteopontin deficiency delays inflammatory infiltration and the onset of muscle regeneration in a mouse model of muscle injury.Dis Model Mech. 6: 197-205.
6. Lin, H. H.et al. (2005) The macrophage F4/80 receptor is required for the induction of antigen-specific efferent regulatory T cells in peripheral tolerance.J. Exp. Med. 201: 1615–1625.
7. Chan, R.J.?et al. (2005) Human somatic PTPN11 mutations induce hematopoietic cell hypersensitivity to granulocyte-macrophage colony stimulating factor.Blood. 105: 3737-3742.
8. Pizza, F.X.?et al. (2005) Neutrophils contribute to muscle injury and impair its resolution after lengthening contractions in mice.J. Physiol. 562:899-913.
9. Tarallo, V.?et al.?(2011) The biflavonoid amentoflavone inhibits neovascularization preventing the activity of proangiogenic vascular endothelial growth factors.J Biol Chem. 286: 19641-51.
10. Rivollier, A.?et al.?(2012) Inflammation switches the differentiation program of Ly6Chi monocytes from antiinflammatory macrophages to inflammatory dendritic cells in the colon.
J Exp Med. 209: 139-55.
11. Hemmi, H.?et al.?(2009) A new triggering receptor expressed on myeloid cells (Trem) family member,Trem-like 4, binds to dead cells and is a DNAX activation protein 12-linkedmarker for subsets of mouse macrophages and dendritic cells.J Immunol. 182:1278-86.
12. Seitz, O.?et al.?(2010) Wound Healing in Mice with High-Fat Diet- or ob Gene-Induced Diabetes-Obesity Syndromes: A Comparative Study.Exp Diabetes Res. 2010: 476969.?
13. Miao, E.A.?et al.?(2011) Caspase-1-induced pyroptosis is an innate immune effector mechanism against intracellular bacteria.Nat Immunol. 11: 1136-42.
14. Wang, X.?et al.?(2011) Activation of the cholinergic antiinflammatory pathway ameliorates obesity-induced inflammation and insulin resistance.Endocrinology. 152: 836-46.
15. Cunningham, O.?et al.?(2009) Microglia and the urokinase plasminogen activator receptor/uPA system ininnate brain inflammation.Glia. 57: 1802-14.
16. Gornicka, A.?et al.?(2012) Adipocyte hypertrophy is associated with lysosomal permeability both in vivo and in vitro: role in adipose tissue inflammation.Am J Physiol Endocrinol Metab. 303: E597-606.
17. Akbarshahi, H.?et al.?(2012) Enrichment of Murine CD68(+)CCR2(+) and CD68(+)CD206(+) Lung Macrophages in Acute Pancreatitis-Associated Acute Lung Injury.PLoS One. 7: e42654.
18. Banda, N.K.?et al.?(1012) Role of C3a receptors, C5a receptors, and complement protein C6 deficiency in collagen antibody-induced arthritis in mice.J Immunol. 188: 1469-78.?
19. Bonde, A.K.?et al.?(2012) Intratumoral macrophages contribute to epithelial-mesenchymal transition in solid tumors.BMC Cancer. 12: 35.
20. Choi, K.M.?et al.?(2010) CD206-positive M2 macrophages that express heme oxygenase-1 protect against diabetic gastroparesis in mice.Gastroenterology. 138: 2399-409,?
21. Tamaki, S.?et al.?(2013) Interleukin-16 promotes cardiac fibrosis and myocardial stiffening in heart failure with preserved ejection fraction.PLoS One. 8: e68893.
22. Kihira, Y.?et al.?(2014) Deletion of hypoxia-inducible factor-1a in adipocytes enhances glucagon-like Peptide-1 secretion and reduces adipose tissue inflammation.PLoS One. 9(4):e93856.
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