皮質(zhì)酮(Corticosterone)是由腎上腺皮質(zhì)分泌的一種糖皮質(zhì)激素，由促腎上腺皮質(zhì)激素(ACTH)刺激腎上腺產(chǎn)生。皮質(zhì)酮通常被認(rèn)為是壓力的生物標(biāo)志物，皮質(zhì)酮的產(chǎn)生隨著壓力的增加而增加。血漿皮質(zhì)酮水平具有晝夜節(jié)律變化，皮質(zhì)酮在睡眠-覺醒周期中起重要作用。
ENZO Corticosterone ELISA kit是一種比色競爭法酶免疫檢測試劑盒，3小時(shí)內(nèi)可以得到檢測結(jié)果。該試劑盒與相關(guān)類固醇的交叉反應(yīng)性較低，在405nm處讀取吸光度。
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●?高靈敏度，可檢測低至27.0 pg/ml的皮質(zhì)酮
●?非種屬特異性，適用于任何物種
●?可用于監(jiān)測動(dòng)物園動(dòng)物的壓力水平
●?高通量，3小時(shí)內(nèi)可得到結(jié)果，可檢測多達(dá)39個(gè)樣本（帶復(fù)孔）
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產(chǎn)品信息
產(chǎn)品貨號(hào) | ADI-900-097/ ADI-901-097 |
產(chǎn)品名稱 | Corticosterone ELISA kit（皮質(zhì)酮ELISA試劑盒） |
規(guī)格 | 96 wells/?5x96 wells |
靈敏度 | 27.0 pg/ml |
檢測范圍 | 32-20,000 pg/ml |
檢測時(shí)間 | 3 hours |
樣本種屬 | Species independent |
交叉反應(yīng) | Corticosterone(100%),Deoxycorticosterone(21.3%), Desoxycorticosterone(21.0%), Progesterone (0.46%),? Testosterone (0.31%), Tetrahydrocorticosterone(0.28%), Aldosterone(0.18%), Cortisol(0.046%) and<0.03%: ?Pregnenolone, Estradiol, Cortisone, 11-dehydrocorticosterone acetate |
樣本類型 | culture supernatants, feces, plasma, serum, and saliva from any species. Cited sample types include cell lysate,? urine and whole blood |
保存溫度 | +4°C |
試劑盒組分 | DxS IgG Microtiter plate, Assay buffer 15 concentrate, Steroid displacement reagent, Conjugate, Antibody, Wash ?buffer concentrate, Standard, pNpp Substrate, Stop solution |
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部分產(chǎn)品引用文獻(xiàn)
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8. Vicarious Social Defeat Increases Conditioned Rewarding Effects of Cocaine and Ethanol Intake in Female Mice: F.R. González, et al.; Biomedicines 11, 502 (2023)?
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10. A non-canonical retina-ipRGCs-SCN-PVT visual pathway for mediating contagious itch behavior: F. Gao, et al.; Cell Rep. 41, 111444 (2022)?
11. ACTH(6-9)-Pro-Gly-Pro ameliorates anxiety-like and depressive-like behaviour and gut mucosal microbiota composition in rats under conditions of chronic restraint stress: A.O. Vorvul, et al.; Neuropeptides 93, 102247 (2022)?
12. Activation of the 5-HT7 receptor and MMP-9 signaling module in the hippocampal CA1 region is necessary for the development of depressive-like behavior: M. Bijata, et al.; Cell Rep. 15, 110532 (2022)
13. Acute stress induces an aberrant increase of presynaptic release of glutamate and cellular activation in the hippocampus of BDNFVal/Met mice: L. Musazzi, et al.; J. Cell. Physiol. 237, 3834 (2022)?
14. Antibiotic-induced microbiota depletion in normally-reared adult rats mimics the neuroendocrine effects of early life stress: R.R. González, et al.; Brain Res. 1793, 148055 (2022)?
15. Anxiolytic-like Effects of the Positive GABAB Receptor Modulator GS39783 Correlate with Mice’s Individual Basal Anxiety and Stress Reactivity: A.O. Bicakci, et al.; Pharmaceuticals 15, 233 (2022)?
16. Cannabidiol prevents depressive-like behaviors through the modulation of neural stem cell differentiation: M. Hou, et al.; Front. Med. 16, 227 (2022)?
17. CD4+/IL 4+ lymphocytes of the lamina propria and substance P promote colonic protection during acute stress: I.M. Arciniega-Martínez, et al.; Mol. Med. Rep. 25, 63 (2022)?
18. Changes in striatal dopamine release, sleep, and behavior during spontaneous Δ-9-tetrahydrocannabinol abstinence in male and female mice: A.J. Kesner, et al.; Neuropsychopharmacology 47, 1537 (2022)?
19. Chronic restraint stress produces sex-specific behavioral and molecular outcomes in the dorsal and ventral rat hippocampus: F.A. Olave, et al.; Neurobiol. Stress 17, 100440 (2022)?
20. Chronic Stress Disrupts the Homeostasis and Progeny Progression of Oligodendroglial Lineage Cells, Associating Immune Oligodendrocytes With Prefrontal Cortex Hypomyelination: A.G. Kokkosis, et al.; Mol. Psychiatry 27, 2833 (2022)
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