瘦素(Leptin)是由ob基因編碼、在脂肪組織中生成的一種脂肪代謝調(diào)控產(chǎn)物，在代謝和調(diào)控體重等方面發(fā)揮重要作用。它通過下丘腦中的瘦素受體發(fā)出信號，降低食欲，增加能量消耗。在外周組織中，瘦素能拮抗胰島素信號傳導(dǎo)，增加脂肪酸氧化，減少胰島β細胞的胰島素分泌，并促進生育。它在脂肪細胞中的表達可以被其他脂肪因子如IL-6（刺激）和TNF-α（抑制）以旁分泌方式調(diào)節(jié)。瘦素缺乏的小鼠表現(xiàn)出嚴重的胰島素抵抗、肥胖和生育能力下降，所有這些都可以通過外源性瘦素給藥而逆轉(zhuǎn)。

?

●?無邊緣效應(yīng)：所有孵育步驟在常溫下進行消除了37°C下蒸發(fā)的風(fēng)險

●?檢測范圍廣：易于定量檢測高水平和低水平瘦素

●?方便：所有試劑保存在4°C

●?快速：僅需3小時就可獲得39個樣本的重復(fù)結(jié)果

●?預(yù)包被板和即用型試劑為您節(jié)省實驗時間

?

?

產(chǎn)品信息

部分產(chǎn)品引用文獻

1. Altered motor, anxiety-related and attentional task performance at baseline associate with multiple gene copies of the vesicular acetylcholine transporter and related protein overexpression in ChAT::Cre+ rats: C.P. Mantanona, et al.; Brain Struct. Funct. 224, 3095 (2019)?

2. Long-term feeding of red algae (Gelidium amansii) ameliorates glucose and lipid metabolism in a high fructose diet-impaired glucose tolerance rat model: H.C. Liu, et al.; J. Food Drug Anal. 25, 543 (2017), Application(s): Determination of leptin, rat plasma?

3. Melatonin supplementation plus exercise behavior ameliorate insulin resistance, hypertension and fatigue in a rat model of type 2 diabetes mellitus: M.M. Rahman, et al.; Biomed. Pharmacother. 92, 606 (2017)?

4. Effect of Intermittent Hypoxia on Arcuate Nucleus in the Leptin-Deficient Rat: J. Ciriello, et al.; Neurosci. Lett. 626, 112 (2016), Application(s): Measured leptin levels in rat aqueous plasma phase?

5. Neonatal treatment with scopolamine butylbromide prevents metabolic dysfunction in male rats: A. Malta, et al.; Sci. Rep. 6, 30745 (2016), Application(s): Leptin level quantification?

6. Impact of prenatal exposure to obesogenic environment on later-life brown and white adipocytes and liver outcomes: L. Bezpalko, et al.; Proc. Shevchenko Sci. Soc. Medicine 41, 33 (2015), Application(s): ELISA using rat serum?

7. Lactobionic acid reduces body weight gain in diet-induced obese rats by targeted inhibition of galectin-1: R. Mukherjee, et al.; Biochem. Biophys. Res. Commun. 463, 1311 (2015), Application(s): ELISA using rat plasma

更多詳情請咨詢Enzo Life Sciences授權(quán)全國代理商-欣博盛生物

全國服務(wù)熱線: 4006-800-892? ? ? ? ? ? 郵箱: market@neobioscience.com?

深圳: 0755-26755892? ? ? 北京: 010-88594029? ? ? ?上海: 021-34613729? ? ??

廣州: 020-87615159? ? ? ? 香港: 852-69410778?

代理品牌網(wǎng)站: www.yuebanme.com?

自主品牌網(wǎng)站: www.neobioscience.net