品牌:Mabtech?
中文名稱:猴IFN-γ酶聯(lián)免疫斑點檢測試劑盒
貨號:3421M-4AST
應(yīng)用:ELISpot
反應(yīng)種屬:小鼠
組分:Biotinylated detection mAb (7-B6-1)
Streptavidin-ALP
anti-CD3 mAb
Substrate (BCIP/NBT-plus)
2 Pre-coated strip clear plates (mAb MT126L)
規(guī)格:2 plates,10 plates
IFN-γ:干擾素-γ (IFN-γ, 也稱 IFN-gamma, IFN-g和Interferon-gamma)主要由活化的T細胞和NK細胞產(chǎn)生。它是一種激活巨噬細胞和內(nèi)皮細胞的促炎細胞因子,也通過影響APC、T和B細胞來調(diào)節(jié)免疫反應(yīng)。輔助T細胞和細胞毒性T細胞產(chǎn)生IF ELISpot N-γ是th1型表型的標志,因此,大量IFN-γ的產(chǎn)生通常與宿主對胞內(nèi)病原體的有效防御有關(guān)。
參考文獻:
Roques, P., et al. (2017). Attenuated and vectored vaccines protect nonhuman primates against Chikungunya virus. JCI Insight.
Sauermann, U., et al. (2017). Vector order determines protection against pathogenic simian immunodeficiency virus infection in a triple component vaccine by balancing CD4 and CD8 T-cell responses. Journal of virology.
Sharpe, S. A., et al. (2018). Refinement and reduction through application of a quantitative score system for estimation of TB-induced disease burden using computed tomography. Lab Anim.
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