DNA損傷有多種檢測方法，其中Stressmarq的DNA損傷檢測試劑盒（SKT-120）主要是通過競爭法ELISA檢測2 8-羥基脫氧鳥苷含量確定DNA損傷的情況。該DNA損傷檢測試劑盒可以檢測的樣本類型包括：細胞裂解液，血漿，尿液。該試劑盒已被85篇文獻引用，產(chǎn)品質(zhì)量穩(wěn)定且精準。
DNA損傷檢測試劑盒（SKT-120）信息：
供應商 | 產(chǎn)品編號 | 產(chǎn)品名稱 | 規(guī)格 |
Stressmarq | SKT-120-96S | DNA Damage (8-OHdG) ELISA Kit | 96 well |
Stressmarq | SKT-120-480S | DNA Damage (8-OHdG) ELISA Kit | 5 x 96 well |
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Stressmarq DNA損傷檢測試劑盒（SKT-120）特點：
1.?檢測時間更短??–?新試劑盒的檢測時間由原來的18小時縮短到僅僅1個小時。
2.?穩(wěn)定性更強?–?舊款試劑盒的乙酰膽堿酯酶和?Ellmans’?試劑盒被替換成?HRP?以及?TMB，增強了穩(wěn)定性，無需儲存在?-20°C。
3.?簡化的實驗步驟??–?直接標記的一抗以及其他組件的改進減少了所需試劑，從而簡化了實驗步驟。
4.?更廣的檢測范圍??–?新試劑盒檢測范圍增加到?0.94?-?60?ng/ml?，這可以減少稀釋步驟并且該范圍可能更適宜生物樣品的讀數(shù)?。
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2021年使用Stressmarq DNA損傷檢測試劑盒（SKT-120）發(fā)表的文獻
●?High throughput data-based, toxicity pathway-oriented development of a quantitative adverse outcome pathway network linking AHR activation to lung damages
Jin, Y. et al (2021) J Hazard Mater. 425:128041
PubMed ID:?34906874?Reactivity?Human?Applications:?Bronchial epithelial cell line 16HBE
●?Effect of Low-Dose Gamma Lipoic Acid on High- Radiation-Dose Induced Radiation and Rat Brain Injuries.
Abdel-Aziz, N., Elkady, A., Elgazzar, E. (2021) Dose Response 2021:1–13
PubMed ID:?34759786?Reactivity?Rat?Applications:?Brain tissue
●?A novel inactivated whole-cell Pseudomonas aeruginosa vaccine that acts through the cGAS-STING pathway.
Ma, C. et al. (2021) Signal Transduct Target Ther (2021) 6:353
PubMed ID:?34593766?Reactivity?P. aeruginosa
●?Systemic Profiles of microRNAs, Redox Balance, and Inflammation in Lung Cancer Patients: Influence of COPD.
Qin, L. et al. (2021) Biomedicines 2021,?9(10), 1347
PubMed ID:?34680465?Reactivity?Human?Applications:?Plasma
●?8-Formylophiopogonanone?B?induces ROS-mediated apoptosis in nasopharyngeal carcinoma CNE-1 cells
Zhang, Y. et al. (2021) Toxicol. Res. Online ahead of print.
PubMed ID:?N/A
●?Experimental evidence that social instability influences rank-specific patterns in oxidative stress in a cichlid fish.
Border, S.E. et al. (2021) J Exp Biol. jeb.237172
PubMed ID:?34495308?Reactivity?Fish
●?Effects of prenatal stress deficiency in C57BL/6 mice on and/or forebrain ATRX cellular metabolism, DNA damage, ATM promoter methylation and gene expression.
Maillet, H. M. (2021) Dalhousie University Masters Thesis
PubMed ID:?N/A?Reactivity?Mouse?Applications:?pre frontal cortex, hippocampus and cerebellum
●?Evaluating the Effects of Commiphora Molmol (Myrrh) Against Oxidative DNA Damage in Human Lymphocytes.
Daradka, H. et al. (2021) IJPSR 12(6): 3143-3149
PubMed ID:?N/A?Reactivity?Human?Applications:?Lymphocytes
●?Curcumin Modulates Nitrosative Stress, Inflammation, and DNA Damage and Protects against Ochratoxin A-Induced Hepatotoxicity and Nephrotoxicity in Rats.
Longobardi, C. et al. (2021) Antioxidants 10(8), 1239
PubMed ID:?34439487?Reactivity?Rat?Applications:?Urine
●?Oxidative Stress in Cerebrospinal Fluid During Treatment in Childhood Acute Lymphoblastic Leukemia.
Dewan, P. et al. (2021) Cureus 13(6): e15997
PubMed ID:?34336488?Reactivity?Human?Applications:?Cerebrospinal Fluid
●?Changes in Urinary Biomarkers of Organ Damage, Inflammation, Oxidative Stress, and Bone Turnover Following a 3000-m Time Trial
Tominaga, T. et al. (2021) Antioxidants 2021, 10, 79
PubMed ID:?33435279?Reactivity?Human?Applications:?Urine
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