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產(chǎn)品名稱:
anti-ZBP1, mAb (Zippy-1)
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別名:
Z-DNA-binding Protein 1; Tumor Stroma and Activated Macrophage Protein DLM-1; DNA-dependent Activator of IFN-regulatory Factors; DAI
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產(chǎn)品描述:
ZBP1 is an interferon inducible protein that binds to cytoplasmic DNA and plays a role in host defense against tumors and pathogens. ZBP1 is highly expressed in lymphatic tissues including lymph node, leukocytes, tonsil, bone marrow and spleen. ZBP1 is an innate immune sensor of Influenza A virus (IAV). ZBP1 regulates NLRP3 (nucleotide and oligomerization domain, leucine-rich repeat-containing protein family, pyrin domain containing 3) inflammasome activation as well as induction of different types of cell death (apoptosis, necroptosis and pyroptosis) during IAV infection.
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反應(yīng)種屬:
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宿主來源:
Purified from concentrated hybridoma tissue culture supernatant.
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實驗應(yīng)用:
ICC, IP, WB
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靶標(biāo)/特異性:
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同種型:
Mouse IgG2a
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推薦稀釋度:
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免疫原:
Recombinant mouse ZBP1 (aa 1-411).
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免疫原種屬:
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克隆性:
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克隆號:
Zippy-1
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純化方式:
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偶聯(lián):
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產(chǎn)品濃度:
1mg/ml
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表達(dá)系統(tǒng):
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陽性對照:
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保存溫度:
-20°C
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運(yùn)輸溫度:
BLUE ICE
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細(xì)胞定位:
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預(yù)期分子量:
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產(chǎn)品形式:
liquid
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存儲溶液:
Liquid. In PBS containing 10% glycerol and 0.02% sodium azide.
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有效期:
Stable for at least 1 year after receipt when stored at -20°C.
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產(chǎn)地:
瑞士
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URL:
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檢測方法:
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樣本類型:
Liquid. In PBS containing 10% glycerol and 0.02% sodium azide.
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產(chǎn)品特點(diǎn):
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純度:
>95% (SDS-PAGE)
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生物活性:
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PubChem CID: