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anti-Periostin [OSF-2], mAb (Stiny-1)
品牌： Adipogen
產(chǎn)品貨號： AG-20B-0033-C100
規(guī)格： 100 ug

報價：
折后價：

數(shù)量： - +
產(chǎn)品詳情
* 以下信息僅供參考，詳情請以原廠網(wǎng)站為準(zhǔn)
  • 產(chǎn)品名稱:
    anti-Periostin [OSF-2], mAb (Stiny-1)
  • 別名:
    Osteoblast-specific Factor 2; OSF-2; Postn
  • 產(chǎn)品描述:
    Periostin is a 90-kDa matricellular protein that consists of a typical signal sequence, followed by a cysteine-rich region, an EMI domain (protein-protein interactions), four tandem fasciclin-like domains that are responsible for integrin binding, and a C-terminal region. Periostin was originally isolated as an osteoblast-specific factor that functions as a cell adhesion molecule for pre-osteoblasts and in osteoblast recruitment, attachment and spreading. Periostin is also involved in many fundamental biological processes such as cell proliferation, cell invasion and angiogenesis. Periostin expression is increased by both transforming growth factor beta1 (TGF-beta1) and bone morphogenetic protein 2 (BMP-2). Changes in periostin expression are commonly detected in various cancers and pre-cancerous conditions, and periostin may be involved in regulating cancer cell activities that contribute to tumorigenesis, cancer progression and metastasis. Periostin has shown to be involved in many aspects of allergic inflammation, such as eosinophil recruitment, airway remodeling, development of a Th2 phenotype and increased expression of inflammatory mediators. It is evaluated as a biomarker for bronchial asthma and airway inflammation.
  • 反應(yīng)種屬:
  • 宿主來源:
    Purified from concentrated hybridoma tissue culture supernatant.
  • 實驗應(yīng)用:
    ELISA, IHC, WB
  • 靶標(biāo)/特異性:
  • 同種型:
    Mouse IgG1kappa
  • 推薦稀釋度:
  • 免疫原:
    Full-length human periostin.
  • 免疫原種屬:
  • 克隆性:
  • 克隆號:
    Stiny-1
  • 純化方式:
  • 偶聯(lián):
  • 產(chǎn)品濃度:
    1mg/ml
  • 表達系統(tǒng):
  • 陽性對照:
  • 保存溫度:
    -20°C
  • 運輸溫度:
    BLUE ICE
  • 細胞定位:
  • 預(yù)期分子量:
  • 產(chǎn)品形式:
    liquid
  • 存儲溶液:
    Liquid. In PBS containing 10% glycerol and 0.02% sodium azide.
  • 有效期:
    Stable for at least 1 year after receipt when stored at -20°C.
  • 產(chǎn)地:
    瑞士
  • 外觀:
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  • 功能與背景:
  • URL:
  • 靈敏度:
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  • 檢測方法:
  • 樣本類型:
    Liquid. In PBS containing 10% glycerol and 0.02% sodium azide.
  • 產(chǎn)品特點:
  • 純度:
    >95% (SDS-PAGE)
  • 生物活性:
  • 內(nèi)毒素水平:
  • 來源:
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  • PubChem CID:
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