P物質(zhì)是一種十一肽激素（RPKPQQFFGLM），是神經(jīng)肽速激肽家族的一員，可介導(dǎo)多種生物活動(dòng)，參與感覺、運(yùn)動(dòng)、情緒等的調(diào)節(jié)，并與焦慮癥、抑郁癥、精神分裂癥的發(fā)病機(jī)理有關(guān)。P物質(zhì)廣泛分布于脊椎動(dòng)物的外周和中樞神經(jīng)系統(tǒng)，在負(fù)責(zé)調(diào)節(jié)情緒的腦區(qū)（杏仁核、導(dǎo)水管周圍灰質(zhì)和下丘腦等）比較豐富，同時(shí)在初級(jí)感覺神經(jīng)元的胞體及神經(jīng)纖維上有較高表達(dá)。
ENZO P物質(zhì)ELISA試劑盒是一種比色競爭法免疫測定試劑盒，用低樣本量即可檢測38個(gè)帶復(fù)孔樣本，3小時(shí)內(nèi)即可獲得結(jié)果。該試劑盒在405 nm處讀取吸光度。
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●?高靈敏度，可檢測低至5.3 pg/ml的P物質(zhì)
●?廣泛的文獻(xiàn)引用
●?高通量，可檢測多達(dá)38個(gè)樣本（帶復(fù)孔）
●?超越半定量蛋白質(zhì)印跡分析的全定量檢測
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產(chǎn)品信息
| 產(chǎn)品貨號(hào) | ADI-900-018A/ ADI-901-018A |
產(chǎn)品名稱 | Substance P ELISA kit（P物質(zhì)ELISA試劑盒） |
規(guī)格 | 96 wells/?5x96 wells |
靈敏度 | 5.3 pg/ml |
檢測范圍 | 9.76 - 10,000 pg/ml |
檢測時(shí)間 | 3 hours |
樣本種屬 | Species independent |
樣本類型 | culture supernatants, plasma, serum, saliva, and urine. Cited sample type includes tissue. |
保存溫度 | Store components at temperatures indicated on the component labeling. |
試劑盒組分 | GxR IgG Microtiter plate, Conjugate, Antibody, Assay buffer, Wash buffer concentrate, Standard, pNpp Substrate, Stop solution |
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部分產(chǎn)品引用文獻(xiàn)
1. A Potential Role for Substance P in West Nile Virus Neuropathogenesis: S.E. Ronca, et al.; Viruses 14, 1961 (2022)
2. Elevated serum substance P during simian varicella virus infection in rhesus macaques: implications for chronic inflammation and adverse cerebrovascular events: A. Bubak, et al.; J. Neurovirol. 26, 945 (2020)
3. Role of the afferent renal nerves in sodium homeostasis and blood pressure regulation in rats: A.A. Frame, et al.; Exp. Physiol. 104, 1306 (2019), Application(s): ELISA using culture supernatants
4. Sensory neuropeptides and their receptors participate in mechano-regulation of murine macrophages: D. Muschter, et al.; Int. J. Mol. Sci. 20, 503 (2019), Application(s): ELISA using culture supernatants
5. Aggressive attempted escape behavior during head-lock restraint reduced reproductive performances in Holstein heifers: V.R. Kasimanickam, et al.; Theriogenology 121, 147 (2018), Application(s): ELISA using bovine serum
6. Effects of castration and a lidocaine-plus-flunixin treatment on growth and indicators of pain, inflammation, and liver function in Korean cattle bull calves: S.J. Park, et al.; Livestock Sci. 216, 61 (2018), Application(s): Bovine Plasma
7. Predictors of beef calf temperament at weaning and its impact on temperament at breeding and reproductive performance: V.R. Kasimanickam, et al.; Reprod. Domest. Anim. 53, 484 (2018), Application(s): ELISA using bovine serum
8. Saliva as a medium to detect and measure biomarkers related to pain: H. Jasim, et al.; Sci. Rep. 8, 3220 (2018), Application(s): ELISA using human plasma and saliva
9. Effects on breathing of agonists to μ-opioid or GABAA receptors dialyzed into the Ventral Respiratory Column of awake and sleeping goats: T.M. Langer, et al.; Respir. Physiol. Neurobiol. 239, 10 (2017)
10. Flunixin meglumine improves pregnancy rate in embryo recipient beef cows with an excitable temperament: R.K. Kasimanickam, et al.; Theriogenology 107, 70 (2017)
11. Acid-Sensing Ion Channel 1a Contributes to Airway Hyperreactivity in Mice: L.R. Reznikov, et al.; PLoS One 11, e0166089 (2016)
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