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Trilink CleanCap? Reagent AG (3' OMe) - (N-7413)產(chǎn)品介紹

2022-03-28
瀏覽次數(shù): 415

窗體頂端

CleanCap?AG (3'OMe)用于mRNA的共轉(zhuǎn)錄,m7(3'OMeG)(5')ppp(5')(2'OMeA)pG

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產(chǎn)品描述:

CleanCap?AG (3' OMe)TriLink公司的專有的共轉(zhuǎn)錄加帽試劑,用于5 '帽端mRNA轉(zhuǎn)錄,形成Cap 1結(jié)構(gòu)。CleanCap的加帽效率高達(dá)98%。Trilink N-7413TrilinkCleanCap?Reagent AG共轉(zhuǎn)錄產(chǎn)品的cap1mRNA要比 mCAPARCA加帽產(chǎn)生的cap0 mRNA活性更好。


產(chǎn)品信息:

產(chǎn)品貨號(hào)N-7413
純度≥95% by AX-HPLC
消光系數(shù)30,539 Lmol-1cm-1?at 255 nm
分子式C33H45N15O24P4?(游離酸)
分子質(zhì)量1159.6
鹽形式Na+
濃度100 mM
溶液組分
推薦的儲(chǔ)存溫度-20°C?或者以下
其他名稱CleanCap??Reagent AG(3'?OMe)?for co-transcriptional capping of mRNA,?m7(3'OMeG)(5’)ppp(5')(2'OMeA)pG
應(yīng)用CRISPR, In vitro Transcription, Recombinases, TALENS, Transposases, Vaccine Development, Zinc Finger Nucleases
主鏈5'-5'-三磷酸
堿基類似物腺苷酸,鳥苷酸
核苷酸種類帽類似物

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產(chǎn)品規(guī)格如下:

供應(yīng)商產(chǎn)品編號(hào)產(chǎn)品名稱規(guī)格
TriLinkN-7413-1CleanCap Reagent??AG3'OMe,??1 umole1 umol
TriLinkN-7413-5CleanCap Reagent??AG3'OMe,??5?umole5?umol
TriLinkN-7413-10CleanCap Reagent??AG3'OMe,??10?umole10 umol
TriLinkN-7413-100CleanCap Reagent??AG3'OMe,??100?umole100?umol


文獻(xiàn)引用;

● Rothgangl, T;Dennis, MK;Lin, PJC;Oka, R;Witzigmann, D;Villiger, L;Qi, W;Hruzova, M;Kissling, L;Lenggenhager, D;Borrelli, C;Egli, S;Frey, N;Bakker, N;Walker, JA;Kadina, AP;Victorov, DV;Pacesa, M;Kreutzer, S;Kontarakis, Z;Moor, A;Jinek, M;Weissman, D;Stoffel, M;van Boxtel, R;Holden, K;Pardi, N;Th . In vivo adenine base editing of PCSK9 in macaques reduces LDL cholesterol levels?

●?Weissman, D;Alameh, MG;de Silva, T;Collini, P;Hornsby, H;Brown, R;LaBranche, CC;Edwards, RJ;Sutherland, L;Santra, S;Mansouri, K;Gobeil, S;McDanal, C;Pardi, N;Hengartner, N;Lin, PJC;Tam, Y;Shaw, PA;Lewis, MG;Boesler, C;?ahin, U;Acharya, P;Haynes, BF;Korber, B;Montefiori, DC; . D614G Spike Mutation Increases SARS CoV-2 Susceptibility to Neutralization?

●?Pandey, RR;Delfino, E;Homolka, D;Roithova, A;Chen, KM;Li, L;Franco, G;V . The Mammalian Cap-Specific m6Am RNA Methyltransferase PCIF1 Regulates Transcript Levels in Mouse Tissues?

●?Mu, Z;Wiehe, K;Saunders, KO;Henderson, R;Cain, DW;Parks, R;Martik, D;Mansouri, K;Edwards, RJ;Newman, A;Lu, X;Xia, SM;Bonsignori, M;Montefiori, D;Han, Q;Venkatayogi, S;Evangelous, T;Wang, Y;Rountree, W;Tam, Y;Barbosa, C;Munir Alam, S;Williams, WB;Pardi, N;Weissman, D;Haynes, BF; . Ability of nucleoside-modified mRNA to encode HIV-1 envelope trimer nanoparticles?

●?Martinez, DR;Schaefer, A;Leist, SR;De la Cruz, G;West, A;Atochina-Vasserman, EN;Parks, R;Barr, M;Li, D;Yount, B;Saunders, KO;Weissman, D;Haynes, BF;Montgomery, SA;Baric, RS; . Chimeric spike mRNA vaccines protect against sarbecovirus challenge in mice



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